The Eversense^® 365 CGM System provides readings within 40 – 400 mg/dL range every 5 minutes.

The following steps outline how to pair your mobile device and smart transmitter.

1. Launch the Eversense^® 365 CGM App and go to the Connect screen (if pairing during installation, when you tap “I have a smart transmitter”, the System Set Up screen is displayed. Tap Connect).
2. Make sure you have an internet connection, and keep the transmitter within 6 feet of your mobile device during the pairing process.
3. Tap the smart transmitter’s soft touch button three times to activate Pairing mode.
4. When the smart transmitter blinks blue, tap the smart transmitter serial number (listed on the back of the smart transmitter) on the CONNECT screen. The app will then begin the searching process.
5. When the app finds your smart transmitter, a BLUETOOTH PAIRING REQUEST pop-up screen appears.
6. The app will display Connected next to the smart transmitter serial number once the pairing is completed.

NOTE: The smart transmitter should not be charging during the pairing process.

Charge the smart transmitter battery daily for about 15 minutes or until the LED is green to ensure you have about 24 hours of battery life. The smart transmitter does not collect information from the sensor or send it to the app while charging. You can charge your smart transmitter by connecting the USB cable to a computer USB port instead of the AC power adapter (wall plug). Using a computer may take longer to fully charge the smart transmitter battery. When you place the smart transmitter back on the sensor site, it may take up to 10 minutes for sensor communication to re-start and for glucose readings to appear in the app.

We find that most people work charging into their daily routine at about the same time each day, for example while taking a shower.

The Eversense^® 365 CGM System measures glucose in interstitial fluid (ISF) between the body’s cells. Physiologic differences between ISF and blood from a finger stick may result in differences in glucose measurements. These differences are especially evident during times of rapid change in blood glucose (e.g., after eating, dosing insulin, or exercising). On average, glucose levels in ISF lag behind glucose levels in blood by several minutes.

The trend arrow on the My Glucose screen of the Eversense^® App screen will give you an indication of which direction the glucose is moving towards, up or down and the rate of change.

There are two steps to ensure proper positioning:

1. When using the adhesive patch to secure the smart transmitter, make sure the button and the LED are lined up in parallel with your arm.
2. Use the PLACEMENT GUIDE screen on the Eversense^® 365 CGM App to confirm connection between the sensor and the transmitter.
• Tap Placement Guide.
• Position the smart transmitter over the sensor so that a connection is confirmed.

For more details on the signal strength of the transmitter and sensor, tap “Show More Details” in the “Linking the Sensor” section.

Initialization Phase (after 24-hour Warm-Up Phase)

During the Initialization Phase, four (4) finger stick blood glucose meter tests are required for calibration.

The 4 calibration tests must be spaced 2 to 12 hours apart, and all 4 tests must be completed within a 36 hour period.

– 1st calibration = 24 hours after sensor insertion.

– 2nd calibration = 2 to 12 hours after 1st successful calibration.

– 3rd calibration = 2 to 12 hours after 2nd successful calibration.

– 4th calibration = 2 to 12 hours after 3rd successful calibration.

Glucose readings will start displaying in the app a few minutes after the 2nd calibration is successfully completed.